The Centre medico-chirurgical de l'Ulcère de Buruli is a hospital in Bouaké, the second largest city on the Ivory Coast, Africa.
The hospital specializes in the treatment of “Buruli Ulcer”, an infection of the skin and soft tissue, caused by Mycobacterium ulcers, which is fairly common in countries with tropical and subtropical climates. Buruli ulcer often starts as a painless swelling (nodule) and can initially manifest itself as a large painless area of plaque or as swelling of the legs, arms or face (edema). Local immunosuppressive properties of the mycolactone toxin enable the disease to progress without any pain and fever. Without treatment or antibiotics, the nodule, plaque or edema ulcerate within 4 weeks with the classical, undermined borders. Occasionally, bones are affected, causing gross deformities often leading to amputation of contaminated limbs.